Near-Infrared Fluorescence Lymphatic Imaging of a Toddler With Congenital Lymphedema.
Identifieur interne : 000350 ( Main/Exploration ); précédent : 000349; suivant : 000351Near-Infrared Fluorescence Lymphatic Imaging of a Toddler With Congenital Lymphedema.
Auteurs : Matthew R. Greives ; Melissa B. Aldrich [États-Unis] ; Eva M. Sevick-Muraca [États-Unis] ; John C. Rasmussen [États-Unis]Source :
- Pediatrics [ 1098-4275 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- imagerie diagnostique : Lymphoedème, Vaisseaux lymphatiques.
- Humains, Imagerie optique, Mâle, Nourrisson.
English descriptors
- KwdEn :
- MESH :
- diagnostic imaging : Lymphatic Vessels, Lymphedema.
- methods : Optical Imaging.
- Humans, Infant, Male.
Abstract
Primary lymphedema in the pediatric population remains poorly diagnosed and misunderstood due to a lack of information on the causation and underlying anatomy of the lymphatic system. Consequently, therapeutic protocols for pediatric patients remain sparse and with little evidence to support them. In an effort to better understand the causation of primary pediatric lymphedema and to better inform clinical care, we report the use of near-infrared fluorescence lymphatic imaging on the extremities of an alert, 21-month-old boy who presented with unilateral right arm and hand lymphedema at birth. The imaging results indicated an intact, apparently normal lymphatic anatomy with no obvious malformation, but with decreased lymphatic contractile function of the affected upper extremity relative to the contralateral and lower extremities. We hypothesized that the lack of contraction of the lymphatic vessels rather than an anatomic malformation was the source of the unilateral extremity swelling, and that compression and manual lymphatic drainage could be effective treatments.
DOI: 10.1542/peds.2015-4456
PubMed: 28356336
Affiliations:
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Consequently, therapeutic protocols for pediatric patients remain sparse and with little evidence to support them. In an effort to better understand the causation of primary pediatric lymphedema and to better inform clinical care, we report the use of near-infrared fluorescence lymphatic imaging on the extremities of an alert, 21-month-old boy who presented with unilateral right arm and hand lymphedema at birth. The imaging results indicated an intact, apparently normal lymphatic anatomy with no obvious malformation, but with decreased lymphatic contractile function of the affected upper extremity relative to the contralateral and lower extremities. We hypothesized that the lack of contraction of the lymphatic vessels rather than an anatomic malformation was the source of the unilateral extremity swelling, and that compression and manual lymphatic drainage could be effective treatments.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Texas</li></region></list><tree><noCountry><name sortKey="Greives, Matthew R" sort="Greives, Matthew R" uniqKey="Greives M" first="Matthew R" last="Greives">Matthew R. Greives</name></noCountry><country name="États-Unis"><region name="Texas"><name sortKey="Aldrich, Melissa B" sort="Aldrich, Melissa B" uniqKey="Aldrich M" first="Melissa B" last="Aldrich">Melissa B. Aldrich</name></region><name sortKey="Rasmussen, John C" sort="Rasmussen, John C" uniqKey="Rasmussen J" first="John C" last="Rasmussen">John C. Rasmussen</name><name sortKey="Sevick Muraca, Eva M" sort="Sevick Muraca, Eva M" uniqKey="Sevick Muraca E" first="Eva M" last="Sevick-Muraca">Eva M. 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